Strain Data Sheet

RBRC00431

Strain Information

Image
BRC No.RBRC00431
TypeWild-derived Inbred
SpeciesMus musculus molossinus
Strain nameMol-Mae/Stm
Former Common nameM. m. molossinus Mae-1, Mol-Mae/Stm
H-2 Haplotype
ES Cell line
Background strainMAE [Mus musculus molossinus]
Appearance
Strain developmentDeveloped by Yoshibumi Matsushima, Saitama Cancer Center.
Strain descriptionアグーチ、日本産野生マウス由来、採取地：岩手県胆沢郡前沢町、採取年：1988年。　1992 F9 -; SPF(F2)
Colony maintenance
References
Gene responsible for deficient activity of the beta subunit of C8, the eighth component of complement, is located on mouse chromosome 4.
Tanaka S, Suzuki T, Sakaizumi M, Harada Y, Matsushima Y, Miyashita N, Fukumori Y, Inai S, Moriwaki K, Yonekawa H
Immunogenetics, 33, 18-23 (1991). 1995474

Japanese wild mice: a rich resource for new disease models.
Matsushima Y
Exp. Anim., 61, 25-33 (2012). 22293669

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
C8bcomplement component 8, beta polypeptide4C8b<0>
  • type II complement component 8 deficiency(MedGEN)

    • Phenotype

    Annotation by Mammalian phenotyhpe ontology
  • normal phenotype(MP:0002873)
    • Detailed phenotype data

    Ordering Information

    供与核酸
    Research application
    提供条件条件を付加しない。
    Depositor松島　芳文（埼玉県立がんセンター研究所）
    Strain Status凍結胚のアイコン凍結胚
    Strain Availability凍結胚より作出したマウスを2~4ヶ月以内に提供可能
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    Click Here for Mouse genomic DNA (RIKEN DNA Bank)

    BRC mice in Publications

    Takada T, Ebata T, Noguchi H, Keane TM, Adams DJ, Narita T, Shin-I T, Fujisawa H, Toyoda A, Abe K, Obata Y, Sakaki Y, Moriwaki K, Fujiyama A, Kohara Y, Shiroishi T.
    The ancestor of extant Japanese fancy mice contributed to the mosaic genomes of classical inbred strains.
    Genome Res 23(8) 1329-38(2013) 23604024
    Bamunusinghe D, Naghashfar Z, Buckler-White A, Plishka R, Baliji S, Liu Q, Kassner J, Oler AJ, Hartley J, Kozak CA.
    Sequence Diversity, Intersubgroup Relationships, and Origins of the Mouse Leukemia Gammaretroviruses of Laboratory and Wild Mice.
    J Virol 90(8) 4186-98(2016) 26865715
    Bamunusinghe D, Liu Q, Lu X, Oler A, Kozak CA.
    Endogenous gammaretrovirus acquisition in Mus musculus subspecies carrying functional variants of the XPR1 virus receptor.
    J Virol 87(17) 9845-55(2013) 23824809
    Mochida K, Hasegawa A, Otaka N, Hama D, Furuya T, Yamaguchi M, Ichikawa E, Ijuin M, Taguma K, Hashimoto M, Takashima R, Kadota M, Hiraiwa N, Mekada K, Yoshiki A, Ogura A.
    Devising assisted reproductive technologies for wild-derived strains of mice: 37 strains from five subspecies of Mus musculus.
    PLoS One 9(12) e114305(2014) 25470728