Strain Data Sheet

RBRC00213

update : 2023-05-22

Information1
Image
BRC No.	RBRC00213
Type	Wild-derived Inbred
Species	Mus musculus musculus
Strain name	PWK
Former Common name
H-2 Haplotype
ES Cell line
Background strain	PWK [Mus musculus musculus]
Appearance	agouti [A/A]
Strain development	チェコのLhotkaにて捕獲された野生個体をもとに育成された系統である。
Strain description	PWKは1974年にチェコ共和国のLhotkaにて捕獲されたMus musculus musculus に属する一つがいのマウスに由来する (Von Deimling et al, 1988) 。この系統は米国Roswell Park Cancer研究所 (Buffalo, NY) の故Chapman博士より理研(筑波) に送られたもので、その後30代以上兄妹交配によって維持されている。C57BL/6とPWKのF1、雑種雄は不妊であることが示されている。
Colony maintenance	兄妹交配による、繁殖は良好。
References	Genetics, 162, 831-840 (2002). 12399393 Proc. Natl. Acad. Sci. USA, 89, 3232-3235 (1992). 1314381 Mamm. Genome, 13, 293-298 (2002). 12115031 Cell, 63, 717-728 (1990). 2225073 Blood, 83, 3225-3231 (1994). 8193357 Dev. Biol., 198, 266-276 (1998). 9659932

Health Report
Examination Date / Room / Rack	2023/02/27Room:4-CRack:B 2022/11/29Room:4-CRack:B 2022/08/29Room:4-CRack:B 2022/05/31Room:4-CRack:B 2022/03/15Room:4-CRack:B 2021/12/13Room:4-CRack:B 2021/09/13Room:4-CRack:B 2021/06/14Room:4-CRack:B

Gene
Gene info

Information2
供与核酸
Research application	Cell Biology Research Developmental Biology Research Genetics Research Reproductive Biology Research
提供条件	条件を付加しない。
Depositor	Roswell Park Cancer Inst.（Roswell Park Cancer Inst.）
Strain Status	生体凍結胚凍結精子
Strain Availability	凍結精子を1ヶ月以内に提供可能凍結胚を1ヶ月以内に提供可能生体マウスを3~6ヶ月以内に提供可能
Additional Info.	Click Here for Mouse genomic DNA (RIKEN DNA Bank) Necessary documents for ordering: Order form (Japanese / English) Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

BRC mice in Publications

Fujiwara K, Igarashi J, Irahara N, Kimura M, Nagase H. New chemically induced skin tumour susceptibility loci identified in a mouse backcross between FVB and dominant resistant PWK. BMC Genet 8 39(2007) 17598916 Horii T, Yanagisawa E, Kimura M, Morita S, Hatada I. Epigenetic differences between embryonic stem cells generated from blastocysts developed in vitro and in vivo. Cell Reprogram 12(5) 551-63(2010) 20818993 Kayashima T, Yamasaki K, Joh K, Yamada T, Ohta T, Yoshiura K, Matsumoto N, Nakane Y, Mukai T, Niikawa N, Kishino T. Atp10a, the mouse ortholog of the human imprinted ATP10A gene, escapes genomic imprinting. Genomics 81(6) 644-7(2003) 12782135 Yamasaki Y, Kayashima T, Soejima H, Kinoshita A, Yoshiura K, Matsumoto N, Ohta T, Urano T, Masuzaki H, Ishimaru T, Mukai T, Niikawa N, Kishino T. Neuron-specific relaxation of Igf2r imprinting is associated with neuron-specific histone modifications and lack of its antisense transcript Air. Hum Mol Genet 14(17) 2511-20(2005) 16037066 Bamunusinghe D, Naghashfar Z, Buckler-White A, Plishka R, Baliji S, Liu Q, Kassner J, Oler AJ, Hartley J, Kozak CA. Sequence Diversity, Intersubgroup Relationships, and Origins of the Mouse Leukemia Gammaretroviruses of Laboratory and Wild Mice. J Virol 90(8) 4186-98(2016) 26865715 Komatsu S, Kiyosawa H, Yoshiki A, Okazaki Y, Yoshino M, Tomaru Y, Watanabe S, Muramatsu M, Kusakabe M, Hayashizaki Y. Identification of seven loci for static glucokinesis and dynamic glucokinesis in mice. Mamm Genome 13(6) 293-8(2002) 12115031 Hayashida K, Kohno S. Hybrid male sterility is caused by mitochondrial DNA deletion. Mol Biol Rep 36(6) 1365-9(2009) 18649010 Yamasaki-Ishizaki Y, Kayashima T, Mapendano CK, Soejima H, Ohta T, Masuzaki H, Kinoshita A, Urano T, Yoshiura K, Matsumoto N, Ishimaru T, Mukai T, Niikawa N, Kishino T. Role of DNA methylation and histone H3 lysine 27 methylation in tissue-specific imprinting of mouse Grb10. Mol Cell Biol 27(2) 732-42(2007) 17101788 Wang Y, Joh K, Masuko S, Yatsuki H, Soejima H, Nabetani A, Beechey CV, Okinami S, Mukai T. The mouse Murr1 gene is imprinted in the adult brain, presumably due to transcriptional interference by the antisense-oriented U2af1-rs1 gene. Mol Cell Biol 24(1) 270-9(2004) 14673161 Fujiwara K, Inagaki Y, Soma M, Ozaki T, Nagase H. Mapping of new skin tumor susceptibility loci by a phenotype-driven congenic approach. Oncol Lett 16(5) 6670-6676(2018) 30405807 Mochida K, Hasegawa A, Otaka N, Hama D, Furuya T, Yamaguchi M, Ichikawa E, Ijuin M, Taguma K, Hashimoto M, Takashima R, Kadota M, Hiraiwa N, Mekada K, Yoshiki A, Ogura A. Devising assisted reproductive technologies for wild-derived strains of mice: 37 strains from five subspecies of Mus musculus. PLoS One 9(12) e114305(2014) 25470728 Morita S, Horii T, Kimura M, Arai Y, Kamei Y, Ogawa Y, Hatada I. Paternal allele influences high fat diet-induced obesity. PLoS One 9(1) e85477(2014) 24416415 Morita S, Nakabayashi K, Kawai T, Hayashi K, Horii T, Kimura M, Kamei Y, Ogawa Y, Hata K, Hatada I. Gene expression profiling of white adipose tissue reveals paternal transmission of proneness to obesity. Sci Rep 6 21693(2016) 26868178

BRC mice in Publications

Fujiwara K, Igarashi J, Irahara N, Kimura M, Nagase H.
New chemically induced skin tumour susceptibility loci identified in a mouse backcross between FVB and dominant resistant PWK.
BMC Genet 8 39(2007) 17598916

Horii T, Yanagisawa E, Kimura M, Morita S, Hatada I.
Epigenetic differences between embryonic stem cells generated from blastocysts developed in vitro and in vivo.
Cell Reprogram 12(5) 551-63(2010) 20818993

Kayashima T, Yamasaki K, Joh K, Yamada T, Ohta T, Yoshiura K, Matsumoto N, Nakane Y, Mukai T, Niikawa N, Kishino T.
Atp10a, the mouse ortholog of the human imprinted ATP10A gene, escapes genomic imprinting.
Genomics 81(6) 644-7(2003) 12782135

Yamasaki Y, Kayashima T, Soejima H, Kinoshita A, Yoshiura K, Matsumoto N, Ohta T, Urano T, Masuzaki H, Ishimaru T, Mukai T, Niikawa N, Kishino T.
Neuron-specific relaxation of Igf2r imprinting is associated with neuron-specific histone modifications and lack of its antisense transcript Air.
Hum Mol Genet 14(17) 2511-20(2005) 16037066

Bamunusinghe D, Naghashfar Z, Buckler-White A, Plishka R, Baliji S, Liu Q, Kassner J, Oler AJ, Hartley J, Kozak CA.
Sequence Diversity, Intersubgroup Relationships, and Origins of the Mouse Leukemia Gammaretroviruses of Laboratory and Wild Mice.
J Virol 90(8) 4186-98(2016) 26865715

Komatsu S, Kiyosawa H, Yoshiki A, Okazaki Y, Yoshino M, Tomaru Y, Watanabe S, Muramatsu M, Kusakabe M, Hayashizaki Y.
Identification of seven loci for static glucokinesis and dynamic glucokinesis in mice.
Mamm Genome 13(6) 293-8(2002) 12115031

Hayashida K, Kohno S.
Hybrid male sterility is caused by mitochondrial DNA deletion.
Mol Biol Rep 36(6) 1365-9(2009) 18649010

Yamasaki-Ishizaki Y, Kayashima T, Mapendano CK, Soejima H, Ohta T, Masuzaki H, Kinoshita A, Urano T, Yoshiura K, Matsumoto N, Ishimaru T, Mukai T, Niikawa N, Kishino T.
Role of DNA methylation and histone H3 lysine 27 methylation in tissue-specific imprinting of mouse Grb10.
Mol Cell Biol 27(2) 732-42(2007) 17101788

Wang Y, Joh K, Masuko S, Yatsuki H, Soejima H, Nabetani A, Beechey CV, Okinami S, Mukai T.
The mouse Murr1 gene is imprinted in the adult brain, presumably due to transcriptional interference by the antisense-oriented U2af1-rs1 gene.
Mol Cell Biol 24(1) 270-9(2004) 14673161

Fujiwara K, Inagaki Y, Soma M, Ozaki T, Nagase H.
Mapping of new skin tumor susceptibility loci by a phenotype-driven congenic approach.
Oncol Lett 16(5) 6670-6676(2018) 30405807

Mochida K, Hasegawa A, Otaka N, Hama D, Furuya T, Yamaguchi M, Ichikawa E, Ijuin M, Taguma K, Hashimoto M, Takashima R, Kadota M, Hiraiwa N, Mekada K, Yoshiki A, Ogura A.
Devising assisted reproductive technologies for wild-derived strains of mice: 37 strains from five subspecies of Mus musculus.
PLoS One 9(12) e114305(2014) 25470728

Morita S, Horii T, Kimura M, Arai Y, Kamei Y, Ogawa Y, Hatada I.
Paternal allele influences high fat diet-induced obesity.
PLoS One 9(1) e85477(2014) 24416415

Morita S, Nakabayashi K, Kawai T, Hayashi K, Horii T, Kimura M, Kamei Y, Ogawa Y, Hata K, Hatada I.
Gene expression profiling of white adipose tissue reveals paternal transmission of proneness to obesity.
Sci Rep 6 21693(2016) 26868178

Information1

Health Report

Gene

Information2

BRC mice in Publications