Strain Data Sheet

RBRC00213

Information1

Image
BRC No.RBRC00213
TypeWild-derived Inbred
SpeciesMus musculus musculus
Strain namePWK
Former Common name
H-2 Haplotype
ES Cell line
Background strainPWK [Mus musculus musculus]
Appearanceagouti [A/A]
Strain developmentチェコのLhotkaにて捕獲された野生個体をもとに育成された系統である。
Strain descriptionPWKは1974年にチェコ共和国のLhotkaにて捕獲されたMus musculus musculus に属する一つがいのマウスに由来する (Von Deimling et al, 1988) 。この系統は米国Roswell Park Cancer研究所 (Buffalo, NY) の故Chapman博士より理研(筑波) に送られたもので、その後30代以上兄妹交配によって維持されている。C57BL/6とPWKのF1、雑種雄は不妊であることが示されている。
Colony maintenance兄妹交配による、繁殖は良好。
ReferencesDev. Biol., 198, 266-276 (1998). 9659932
Cell, 63, 717-728 (1990). 2225073
Blood, 83, 3225-3231 (1994). 8193357
Proc. Natl. Acad. Sci. USA, 89, 3232-3235 (1992). 1314381
Mamm. Genome, 13, 293-298 (2002). 12115031
Genetics, 162, 831-840 (2002). 12399393

Health Report

Examination Date / Room / Rack2022/08/29Room:4-CRack:B
2022/05/31Room:4-CRack:B
2022/03/15Room:4-CRack:B
2021/12/13Room:4-CRack:B
2021/09/13Room:4-CRack:B
2021/06/14Room:4-CRack:B
2021/03/29Room:4-CRack:B
2021/01/05Room:4-CRack:B
2020/10/05Room:4-CRack:B

Gene

Gene info

Information2

供与核酸
Research applicationCell Biology Research
Developmental Biology Research
Genetics Research
Reproductive Biology Research
提供条件条件を付加しない。
DepositorRoswell Park Cancer Inst.(Roswell Park Cancer Inst.)
Strain Status生体のアイコン生体
凍結胚のアイコン凍結胚
凍結精子のアイコン凍結精子
Strain Availability凍結精子を1ヶ月以内に提供可能
凍結胚を1ヶ月以内に提供可能
生体マウスを3~6ヶ月以内に提供可能
Additional Info.Click Here for Mouse genomic DNA (RIKEN DNA Bank)
Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

BRC mice in Publications

Fujiwara K, Igarashi J, Irahara N, Kimura M, Nagase H.
New chemically induced skin tumour susceptibility loci identified in a mouse backcross between FVB and dominant resistant PWK.
BMC Genet 8 39(2007) 17598916

Horii T, Yanagisawa E, Kimura M, Morita S, Hatada I.
Epigenetic differences between embryonic stem cells generated from blastocysts developed in vitro and in vivo.
Cell Reprogram 12(5) 551-63(2010) 20818993

Kayashima T, Yamasaki K, Joh K, Yamada T, Ohta T, Yoshiura K, Matsumoto N, Nakane Y, Mukai T, Niikawa N, Kishino T.
Atp10a, the mouse ortholog of the human imprinted ATP10A gene, escapes genomic imprinting.
Genomics 81(6) 644-7(2003) 12782135

Yamasaki Y, Kayashima T, Soejima H, Kinoshita A, Yoshiura K, Matsumoto N, Ohta T, Urano T, Masuzaki H, Ishimaru T, Mukai T, Niikawa N, Kishino T.
Neuron-specific relaxation of Igf2r imprinting is associated with neuron-specific histone modifications and lack of its antisense transcript Air.
Hum Mol Genet 14(17) 2511-20(2005) 16037066

Bamunusinghe D, Naghashfar Z, Buckler-White A, Plishka R, Baliji S, Liu Q, Kassner J, Oler AJ, Hartley J, Kozak CA.
Sequence Diversity, Intersubgroup Relationships, and Origins of the Mouse Leukemia Gammaretroviruses of Laboratory and Wild Mice.
J Virol 90(8) 4186-98(2016) 26865715

Komatsu S, Kiyosawa H, Yoshiki A, Okazaki Y, Yoshino M, Tomaru Y, Watanabe S, Muramatsu M, Kusakabe M, Hayashizaki Y.
Identification of seven loci for static glucokinesis and dynamic glucokinesis in mice.
Mamm Genome 13(6) 293-8(2002) 12115031

Hayashida K, Kohno S.
Hybrid male sterility is caused by mitochondrial DNA deletion.
Mol Biol Rep 36(6) 1365-9(2009) 18649010

Yamasaki-Ishizaki Y, Kayashima T, Mapendano CK, Soejima H, Ohta T, Masuzaki H, Kinoshita A, Urano T, Yoshiura K, Matsumoto N, Ishimaru T, Mukai T, Niikawa N, Kishino T.
Role of DNA methylation and histone H3 lysine 27 methylation in tissue-specific imprinting of mouse Grb10.
Mol Cell Biol 27(2) 732-42(2007) 17101788

Wang Y, Joh K, Masuko S, Yatsuki H, Soejima H, Nabetani A, Beechey CV, Okinami S, Mukai T.
The mouse Murr1 gene is imprinted in the adult brain, presumably due to transcriptional interference by the antisense-oriented U2af1-rs1 gene.
Mol Cell Biol 24(1) 270-9(2004) 14673161

Fujiwara K, Inagaki Y, Soma M, Ozaki T, Nagase H.
Mapping of new skin tumor susceptibility loci by a phenotype-driven congenic approach.
Oncol Lett 16(5) 6670-6676(2018) 30405807

Mochida K, Hasegawa A, Otaka N, Hama D, Furuya T, Yamaguchi M, Ichikawa E, Ijuin M, Taguma K, Hashimoto M, Takashima R, Kadota M, Hiraiwa N, Mekada K, Yoshiki A, Ogura A.
Devising assisted reproductive technologies for wild-derived strains of mice: 37 strains from five subspecies of Mus musculus.
PLoS One 9(12) e114305(2014) 25470728

Morita S, Horii T, Kimura M, Arai Y, Kamei Y, Ogawa Y, Hatada I.
Paternal allele influences high fat diet-induced obesity.
PLoS One 9(1) e85477(2014) 24416415

Morita S, Nakabayashi K, Kawai T, Hayashi K, Horii T, Kimura M, Kamei Y, Ogawa Y, Hata K, Hatada I.
Gene expression profiling of white adipose tissue reveals paternal transmission of proneness to obesity.
Sci Rep 6 21693(2016) 26868178