RBRC00165

Information1

Image
BRC No.RBRC00165
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.129S4-Zic2<tm1Jaru>/JaruRbrc
Former Common nameC57BL/6N-Kd(Zic2), Zic2 Knockdown mouse
H-2 Haplotype
ES Cell line
Background strainC57BL/6N
Appearanceblack
Strain development
Strain description
Colony maintenance
ReferencesJ. Neurosci., 22, 218-225 (2002). 11756505
Proc. Natl. Acad. Sci. USA, 97, 1618-1623 (2000). 10677508

Health Report

Examination Date / Room / RackNo Data

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Zic2zinc finger protein of the cerebellum 214Zic2<tm1Jaru>targeted mutation 1, Jun Aruga

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)14mouse phosphoglycerate kinase promoter (PGK promoter)

Information2

供与核酸mouse Zic2 (Zic finger protein of the cerebellum 2) genomic DNA, E. coli neo, mouse phosphoglycerate kinase promoter (PGK promoter)
Research applicationNeurobiology Research
提供条件条件を付加する。利用者は事前に寄託者の提供承諾書を得る。
研究成果の公表にあたって寄託者の指定する文献を引用する。Proc. Natl. Acad. Sci. USA, 97, 1618-1623 (2000).
Depositor有賀 純(理化学研究所脳科学総合研究センター)
Strain Status凍結胚のアイコン凍結胚
凍結精子のアイコン凍結精子
Strain Availability凍結胚より作出したマウスを2~4ヶ月以内に提供可能
凍結精子を1ヶ月以内に提供可能
凍結胚を1ヶ月以内に提供可能
Additional Info.Lab HP

BRC mice in Publications

Garc a-Frigola C, Carreres MI, Vegar C, Mason C, Herrera E.
Zic2 promotes axonal divergence at the optic chiasm midline by EphB1-dependent and -independent mechanisms.
Development 135(10) 1833-41(2008) 18417618

Garc a-Frigola C, Herrera E.
Zic2 regulates the expression of Sert to modulate eye-specific refinement at the visual targets.
EMBO J. 29(18) 3170-83(2010) 20676059

S nchez-Arrones L, Nieto-Lopez F, S nchez-Camacho C, Carreres MI, Herrera E, Okada A, Bovolenta P.
Shh/Boc signaling is required for sustained generation of ipsilateral projecting ganglion cells in the mouse retina.
J. Neurosci. 33(20) 8596-607(2013) 23678105