Strain Data Sheet

RBRC12299

Strain Information

Image
BRC No.RBRC12299
TypeCRISPR/Cas9 (Transgene)Cartagena
SpeciesMus musculus
Strain nameB6J-Cacna1c<em1(Y1709F)Smpmy>
Former Common nameCaV1.2_Y1709F
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References

Health Report

Examination Date / Room / Rack2025/11/10Room:3-ARack:ISentinel mouse program

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Cacna1c
MGI:103013		calcium channel, voltage-dependent, L type, alpha 1C subunit6Cacna1c<em1(Y1709F)Smpmy> endonuclease mediated mutation 1,
  • Brugada syndrome 3(MedGEN)

  • long qt syndrome 8(MedGEN)

  • Timothy syndrome(DisGeNET, MedGEN)

    • Phenotype

    Phenotype annotation from literatures by Mammalian phenotype ontology
    Detailed phenotype data

    Ordering Information

    Donor DNACACNA1C gene harboring a Y1709F point mutation introduced in mice
    Research application
    Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. 後日指定
    DepositorMitsuhiko Yamada (Shinshu University)
    Strain Statusan icon for Live miceLive mice
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityLive mouse (more than 6 months)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: CRISPR/Cas9 genome edited bioresources (Japanese / English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data