Strain Data Sheet

RBRC12161

Strain Information

Image
BRC No.RBRC12161
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6N-Avp<tm1.1Ksak>
Former Common nameAVP-floxed
H-2 Haplotype
ES Cell lineRENKA [C57BL/6NCrlCrlj]
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
Vasopressin Expressed in Hypothalamic CRF Neurons Causes Impaired Water Diuresis in Secondary Adrenal Insufficiency.
Satoshi Yamagata, Ashraf H Talukder, Shingo Murasawa, Kanako Niioka, Naoya Kumagai, Mao Takagi, Meiko Kawamura, Rie Natsume, Manabu Abe, Katsuya Uchida, Tatsuya Sato, Akira Kurose, Kazunori Kageyama, Makoto Daimon, Kenji Sakimura, Keiichi Itoi
Endocrinology, 164(8):bqad109 (2023). 37450603

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Avp
MGI:88121		arginine vasopressin2Avp<tm1.1Ksak> targeted mutation 1.1, Kenji Sakimura
  • central diabetes insipidus(DisGeNET)

  • neurohypophyseal diabetes insipidus(MedGEN)
    • Frt yeast FRT (flippase recombination target) site2Frt
    loxP phage P1 loxP2loxP

    Phenotype

    Phenotype annotation from literatures by Mammalian phenotype ontology
    Detailed phenotype data

    Ordering Information

    Donor DNAP1 phage loxP, Yeast Frt
    Research applicationCre/loxP system
    FLP/frt system
    Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Endocrinology, 164(8):bqad109 (2023).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
    DepositorKeiichi Itoi (Tohoku University)
    Strain Statusan icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovery and QC required prior to distribution
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)

    BRC mice in Publications

    No Data