Strain Data Sheet

RBRC12124

Strain Information

Image
BRC No.RBRC12124
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameB6-Tg(Il4-hCD2)21Kubo
Former Common nameIL4 hCD2 reporter mouse, IL-4-hCD2 BAC Tg
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
Protective neutralizing influenza antibody response in the absence of T follicular helper cells.
Kosuke Miyauchi, Akiko Sugimoto-Ishige, Yasuyo Harada, Yu Adachi, Yoshiko Usami, Tomohiro Kaji, Kentaro Inoue, Hideki Hasegawa, Takashi Watanabe, Atsushi Hijikata, Satoshi Fukuyama, Tadashi Maemura, Mariko Okada-Hatakeyama, Osamu Ohara, Yoshihiro Kawaoka, Yoshimasa Takahashi, Toshitada Takemori, Masato Kubo
Nat. Immunol., 17(12) 1447-1458 (2016). 27798619

Health Report

Examination Date / Room / Rack2025/11/04Room:3-3Rack:DSentinel mouse program
2025/08/18Room:3-3Rack:DSentinel mouse program
2025/06/09Room:3-3Rack:DSentinel mouse program

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
CD2 CD2 (human)UNCD2
Ires internal ribosomal entry site (EMCV)UN
loxP phage P1 loxPUNloxP
SV40 polyAUN

Phenotype

Phenotype annotation from literatures by Mammalian phenotype ontology
Detailed phenotype data

Ordering Information

Donor DNAmouse Il4 DNA fragment(exon4), ECMV IRES, human CD2 cDNA, SV40 polyA, Phage P1 loxP site from pBACe3.6(RPCI) vector
Research applicationCre/loxP system
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Nat. Immunol., 17(12) 1447-1458 (2016).
DepositorMasato Kubo (RIKEN IMS)
Strain Statusan icon for Live miceLive mice
an icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityCryopreserved sperm (within 1 month)
Live mouse (1 to 3 months)
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data