Strain Data Sheet

RBRC11936

Strain Information

Image
BRC No.RBRC11936
TypeTargeted Mutation CongenicCartagena
SpeciesMus musculus
Strain nameB6.Cg-Card9<tm1Saito>
Former Common nameCARD9 KO
H-2 Haplotype
ES Cell lineR1 [(129X1/SvJ x 129S1/Sv)F1-Kitl<+>]
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors.
Hiromitsu Hara, Chitose Ishihara, Arata Takeuchi, Takayuki Imanishi, Liquan Xue, Stephan W Morris, Masanori Inui, Toshiyuki Takai, Akira Shibuya, Shinobu Saijo, Yoichiro Iwakura, Naohito Ohno, Haruhiko Koseki, Hiroki Yoshida, Josef M Penninger, Takashi Saito
Nat. Immunol., 8(6):619-29 (2007). 17486093

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Card9
MGI:2685628		caspase recruitment domain family, member 92Card9<tm1Saito> targeted mutation 1, Takashi Saito
  • predisposition to invasive fungal disease due to CARD9 deficiency(MedGEN)
    • neo neomycin resistance gene (E. coli)2

    Phenotype

    Phenotype annotation from literatures by Mammalian phenotype ontology
    Detailed phenotype data

    Ordering Information

    Donor DNAE. coli Neomycin resistant gene
    Research applicationImmunology and Inflammation Research
    Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Nat. Immunol., 8(6):619-29 (2007).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
    DepositorTakashi Saito (RIKEN IMS)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovery and QC required prior to distribution
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)

    BRC mice in Publications

    No Data