Strain Data Sheet

RBRC11923

Strain Information

Image
BRC No.RBRC11923
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.129-Il31<tm1(lacZ)Sabu>
Former Common nameIL-31 deficient mice : #30 (-/-)
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
Regulation of Th2 responses by different cell types expressing the interleukin-31 receptor.
Saburo Saito, Ayana Aoki, Iwao Arai, Shinya Takaishi, Haruyasu Ito, Nobutake Akiyama, Hiroshi Kiyonari
Allergy Asthma Clin. Immunol., 13:23 (2017). doi: 10.1186/s13223-017-0194-9. 28428802

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Frtyeast FRT (flippase recombination target) site5Frt
Frtyeast FRT (flippase recombination target) site5Frt
Il31interleukin 315Il31
lacZbeta-galactosidase (E. coli)5
lox71mutant lox sequence5lox71
loxPphage P1 loxP5loxP
neoneomycin resistance gene (E. coli)5mouse phosphoglycerate kinase promoter (PGK promoter)

Phenotype

Annotation by Mammalian phenotyhpe ontology
Detailed phenotype data

Ordering Information

Donor DNAPhage P1 lox71 site, E. coli LacZ, rabbit β-globin polyadenylation signal (Gil and Proudfoot, 1987), yeast FRT (flippase recombination target) sites, mouse phosphoglycerate kinase 1 promoter, E. coli neo, Phage P1 loxP site, mouse Il31 genomic DNA
Research applicationCre/loxP system
FLP/frt system
Fluorescent Proteins/lacZ System
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Allergy Asthma Clin Immunol., 13:23 (2017). doi: 10.1186/s13223-017-0194-9.In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
DepositorNobutake Akiyama (The Jikei University School of Medicine)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data