Strain Data Sheet

RBRC11922

Strain Information

Image
BRC No.RBRC11922
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.129-Il31ra<tm1(lacZ)Sabu>
Former Common nameIL-31RA-defcient mice:#58RA(-/-)
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
Regulation of Th2 responses by different cell types expressing the interleukin-31 receptor.
Saburo Saito, Ayana Aoki, Iwao Arai, Shinya Takaishi, Haruyasu Ito, Nobutake Akiyama, Hiroshi Kiyonari
Allergy Asthma Clin. Immunol., 13:23 (2017). doi: 10.1186/s13223-017-0194-9. 28428802

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Frtyeast FRT (flippase recombination target) site13Frt
  • amyloidosis, primary localized cutaneous, 2(MedGEN)
    • Frtyeast FRT (flippase recombination target) site13Frt
  • amyloidosis, primary localized cutaneous, 2(MedGEN)
    • Il31rainterleukin 31 receptor A13Il31ratargeted mutation 1,
  • amyloidosis, primary localized cutaneous, 2(MedGEN)
    • lacZbeta-galactosidase (E. coli)13
  • amyloidosis, primary localized cutaneous, 2(MedGEN)
    • lox71mutant lox sequence13lox71
  • amyloidosis, primary localized cutaneous, 2(MedGEN)
    • loxPphage P1 loxP13loxP
  • amyloidosis, primary localized cutaneous, 2(MedGEN)
    • neoneomycin resistance gene (E. coli)13mouse phosphoglycerate kinase promoter (PGK promoter)
  • amyloidosis, primary localized cutaneous, 2(MedGEN)

    • Phenotype

    Annotation by Mammalian phenotyhpe ontology
    Detailed phenotype data

    Ordering Information

    Donor DNAPhage P1 lox71 site, E. coli LacZ, rabbit β-globin polyadenylation signal (Gil and Proudfoot, 1987), yeast FRT (flippase recombination target) sites, mouse phosphoglycerate kinase 1 promoter, E. coli neo, Phage P1 loxP site, mouse Il31ra genomic DNA
    Research applicationCre/loxP system
    FLP/frt system
    Fluorescent Proteins/lacZ System
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Allergy Asthma Clin Immunol., 13:23 (2017). doi: 10.1186/s13223-017-0194-9.In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. In publishing the research results obtained by use of B6.129-Il31ra<tm1(lacZ)Sabu> mice, a citation of the following literature(s) designated by the DEPOSITOR is requested.
    Accession No. : CDB1012K and Website :
    https://large.riken.jp/distribution/mutant-list.html.
    In publishing the research results obtained by use of B6.129-Il31ra<tm1(lacZ)Sabu> mice, a citation of the following literature(s) designated by the DEPOSITOR is requested. Saito S,
    Aoki A, Arai I, Takaishi S, Ito H, Akiyama N, Kiyonari H. (2017) Regulation of Th2 responses by different cell types expressing the interleukin 31 receptor. Allergy, Asthma & Clinical
    Immunology. DOI 10.1186/s13223-017-0194-9.
    In publishing the research results obtained by use of B6.129-Il31ra<tm1(lacZ)Sabu> mice, send the information to mutant.bdr@riken.jp.
    DepositorNobutake Akiyama (The Jikei University School of Medicine)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data