Strain Data Sheet

RBRC11810

Strain Information

Image
BRC No.RBRC11810
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain name129S6/SvEv-Mir124a-2<tm1.1Tfur>
Former Common namemiR-124a-2 KO
H-2 Haplotype
ES Cell lineTC1 [129S6/SvEvTac]
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
Multiple knockout mouse and embryonic stem cell models reveal the role of miR-124a in neuronal maturation.
Taro Chaya, Yamato Maeda, Ryo Sugimura, Daisuke Okuzaki, Satoshi Watanabe, Leah R Varner, Daisuke Motooka, Daichi Gyoten, Haruka Yamamoto, Hidemasa Kato, Takahisa Furukawa
J. Biol. Chem., 298(9):102293.(2022). doi: 10.1016/j.jbc.2022.102293. 35868558

Health Report

Examination Date / Room / Rack2024/05/27Room:4-CRack:J
2024/02/26Room:4-CRack:J
2023/11/27Room:4-CRack:J

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Mir124a-2microRNA 124a-23Mir124a-2targeted mutation 1.1, Takahisa Furukawa
loxPphage P1 loxP3loxP

Phenotype

Annotation by Mammalian phenotyhpe ontology
Detailed phenotype data

Ordering Information

Donor DNAphage P1 loxP site, mouse Mir124a-2 genomic DNA
Research applicationCre/loxP system
Neurobiology Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Biol. Chem., 298(9):102293.(2022). doi: 10.1016/j.jbc.2022.102293.The RECIPIENT must contact to the DEPOSITOR and contact an MTA with Osaka University.
DepositorTakahisa Furukawa (Osaka University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved embryos (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data