Strain Data Sheet

RBRC11737

Strain Information

Image
BRC No.RBRC11737
TypeCRISPR/Cas9Cartagena
SpeciesMus musculus
Strain nameB6-Cfap53<em1Hmd>
Former Common nameCfap53/Ccdc11(dex2)#6
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
CFAP53 regulates mammalian cilia-type motility patterns through differential localization and recruitment of axonemal dynein components.
Takahiro Ide, Wang Kyaw Twan, Hao Lu, Yayoi Ikawa, Lin-Xenia Lim, Nicole Henninger, Hiromi Nishimura, Katsuyoshi Takaoka, Vijay Narasimhan, Xiumin Yan, Hidetaka Shiratori, Sudipto Roy, Hiroshi Hamada
PLoS Genet., 16(12):e1009232 (2020). 33347437

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Cfap53
MGI:1921703		cilia and flagella associated protein 5318Cfap53<em1Hmd> endonuclease-mediated mutation 1, Hiroshi Hamada
  • heterotaxy, visceral, 6, autosomal(MedGEN)

    • Phenotype

    Phenotype annotation from literatures by Mammalian phenotype ontology
    Detailed phenotype data

    Ordering Information

    Donor DNAStreptococcus pyogenes tracrRNA, crRNA, Cas9, mousea part of Cfap53/Ccdc11 gene
    Research application
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. PLoS Genet., 16(12):e1009232 (2020). doi: 10.1371/journal.pgen.1009232.
    DepositorHiroshi Hamada (RIKEN BDR)
    Strain Statusan icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovery and QC required prior to distribution
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: CRISPR/Cas9 genome edited bioresources (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    BRC mice in Publications

    No Data