Strain Data Sheet
RBRC11707
Strain Information | |
|---|---|
| Image | |
| BRC No. | RBRC11707 |
| Type | Targeted Mutation |
| Species | Mus musculus |
| Strain name | C.129X1(B6)-Pirb<tm1Ttk> |
| Former Common name | PirB-KO mice |
| H-2 Haplotype | |
| ES Cell line | RW4 [129X1/SvJ] |
| Background strain | |
| Appearance | |
| Strain development | |
| Strain description | |
| Colony maintenance | |
| References | Impaired dendritic cell maturation and increased T(H)2 responses in PIR-B(-/-) mice. Azusa Ujike, Kazuhiko Takeda, Akira Nakamura, Shin Ebihara, Kenichi Akiyama, Toshiyuki Takai Nat. Immunol., 3(6):542-8 (2002). 12021780 |
Health Report | |
|---|---|
| Examination Date / Room / Rack | 2025/02/25Room:4-BRack:ISentinel mouse program 2024/11/25Room:4-BRack:ISentinel mouse program 2024/08/26Room:4-BRack:ISentinel mouse program 2024/05/27Room:4-BRack:ISentinel mouse program |
Gene | |||||||
|---|---|---|---|---|---|---|---|
| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| Pirb MGI:894311 | paired Ig-like receptor B | 7 | Pirb<tm1Ttk> MGI:2180757 | targeted mutation 1, Toshiyuki Takai | |||
| neo | neomycin resistance gene (E. coli) | 7 | |||||
Phenotype | |
|---|---|
| Phenotype annotation from literatures by Mammalian phenotype ontology | |
| Detailed phenotype data | |
Ordering Information | |
|---|---|
| Donor DNA | herpes simplex virus thymidine kinase promoter (HSV tk promoter), Escherichia coli Neo, mouse Pirb genomic DNA |
| Research application | Immunology and Inflammation Research Neurobiology Research |
| Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Nat. Immunol., 3(6):542-8 (2002). doi: 10.1038/ni801. |
| Depositor | Toshiyuki Takai (Tohoku University) |
| Strain Status |  Frozen embryos Frozen sperm |
| Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
| Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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| No Data |