Strain Data Sheet

RBRC11704

Strain Information

Image
BRC No.RBRC11704
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.129P2-Tyrobp<tm1Ttk>
Former Common nameDAP12-KO mice
H-2 Haplotype
ES Cell lineE14 [129P2/OlaHsd]
Background strain
Appearance
Strain development
Strain description
Colony maintenance
References
Osteopetrosis and thalamic hypomyelinosis with synaptic degeneration in DAP12-deficient mice.
Tomonori Kaifu, Jin Nakahara, Masanori Inui, Kenichi Mishima, Toshihiko Momiyama, Mitsuji Kaji, Akiko Sugahara, Hisami Koito, Azusa Ujike-Asai, Akira Nakamura, Kiyoshi Kanazawa, Kyoko Tan-Takeuchi, Katsunori Iwasaki, Wayne M Yokoyama, Akira Kudo, Michihiro Fujiwara, Hiroaki Asou, Toshiyuki Takai
J. Clin. Invest., 111 (3) 323-32 (2003). 12569157

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Tyrobp
MGI:1277211		TYRO protein tyrosine kinase binding protein7Tyrobp<tm1Ttk>
MGI:2450834		targeted mutation 1, Toshiyuki Takai
  • polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 1(MedGEN)
    • neo neomycin resistance gene (E. coli)7

    Phenotype

    Phenotype annotation from literatures by Mammalian phenotype ontology
    Detailed phenotype data

    Ordering Information

    Donor DNAEscherichia coli Neo
    Research applicationDevelopmental Biology Research
    Mouse Models for Human Disease
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Clin. Invest., 111(3):323-32 (2003). doi: 10.1172/JCI16923.
    DepositorToshiyuki Takai (Tohoku University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovery and QC required prior to distribution
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    BRC mice in Publications

    No Data