Strain Information | |
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Image | |
BRC No. | RBRC11688 |
Type | CRISPR/Cas9 (Transgene) |
Species | Mus musculus |
Strain name | B6;Cg-Oxtr<em3(3xPA)Yinn> |
Former Common name | Oxtr<3xPA> |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Deposited by Yukiko U. Inoue and Takayoshi Inoue, National Center of Neurology and Psychiatry in 2022. This strain was generated using fertilized eggs derived from (C57BL/6 x C3H)F1. Mixed genetic background. |
Strain description | Knockin mice of 3 copies of PA tag at the C-terminus of the Oxtr gene. Homozygous mice are fertile. |
Colony maintenance | |
References | Targeting Neurons with Functional Oxytocin Receptors: A Novel Set of Simple Knock-In Mouse Lines for Oxytocin Receptor Visualization and Manipulation. Yukiko U Inoue, Hideki Miwa, Kei Hori, Ryosuke Kaneko, Yuki Morimoto, Eriko Koike, Junko Asami, Satoshi Kamijo, Mitsuhiko Yamada, Mikio Hoshino, Takayoshi Inoue eNeuro, 9(1):ENEURO.0423-21.2022 (2022). 35082173 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Oxtr | oxytocin receptor | 6 | Oxtr | endonuclease-mediated mutation 3, Yukiko U Inoue | |||
PA | PA tag (GVAMPGAEDDVV) (synthetic) human Podoplanin | 6 | PA |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | human Podoplanin PA-tag sequence |
Research application | |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. eNeuro. Feb 15;9(1):ENEURO.0423-21.2022 (2022)For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Takayoshi Inoue (National Center of Neurology and Psychiatry) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- Mouse of the Month Sep 2023 |
BRC mice in Publications |
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No Data |