Strain Data Sheet



BRC No.RBRC11571
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.129-Gba2<tm1Rus>/Yhir
Former Common nameGBA2 KO
H-2 Haplotype
ES Cell line
Background strain
Strain developmentDeposited by Hisako Akiyama in 2021 with permission from Dr. Dagmar Wachten. This strain was generated using ES cells derived from 129S6/SvEv and then backcrossed to C57BL/6J for 10 generations.
Strain descriptionGba2 knockout mice. Exons 5-10 are deleted.
Colony maintenance
ReferencesJ. Biol. Chem., 295(16):5257-5277 (2020). 32144204
J. Clin. Invest., 116(11):2985-94 (2006). 17080196

Health Report

Examination Date / Room / Rack


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Gba2glucosidase beta 24Gba2<tm1Rus>targeted mutation 1, David W Russell

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP4loxP


Donor DNAP1ファージ loxP
Research applicationCre/loxP system
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Biol. Chem., 295(16):5257-5277 (2020).
DepositorHiroyuki Kamiguchi (RIKEN)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data