Strain Data Sheet

RBRC11565

Information1

Image
BRC No.RBRC11565
TypeCRISPR/Cas9 (Transgene)Cartagena
SpeciesMus musculus
Strain nameC.Cg-Ace2<em1(ACE2)Okt>
Former Common namehACE2KI_NCGM
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeposited by Tadashi Oakmura, National Center for Global Health and Medicine, NCGM in 2021. This strain was generated using fertilized eggs derived from Slc:BDF1 x C57BL/6JJcl. Mice were backcrossed to BALB/c for 8 generations.
Strain descriptionKnockin mice of human ACE2 at the Ace2 locus.
Colony maintenance
References

Health Report

Examination Date / Room / Racknull

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Ace2angiotensin I converting enzyme (peptidyl-dipeptidase A) 2XAce2<em1(ACE2)Okt>

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
ACE2angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (human)XACE2

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
HBB2rabbit beta-globin polyA signalXHBB2

Information2

Donor DNAhuman ACE2 cDNA, rabbit beta-globin poly(A) signal sequence, mouse Ace2 genomic DNA
Research applicationImmunology and Inflammation Research
Virology Research
covid19_infection
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. 後日指定For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR.
DepositorTadashi Okamura (National Center for Global Health and Medicine)
Strain Statusan icon for Live miceLive mice
an icon for Frozen spermFrozen sperm
Strain AvailabilityLive mouse (3 to 6 months)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: CRISPR/Cas9 genome edited bioresources (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data