Strain Data Sheet


Strain Information

BRC No.RBRC11546
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129S-Ppme1<tm1Crv>
Former Common namePpme1 +/- mouse
H-2 Haplotype
ES Cell line
Background strain
Strain developmentDeposited by Benjamin F Cravatt, The Scripps Research Institute in 2021. This strain was generated ES cells derived from 129S6/SvEv and crossed to C57BL/6. Mixed genetic background.
Strain descriptionPpme1 knock out mice. Exon 7 was replaced with a neo cassette. Homozygous mutants are neonatally lethal.
Colony maintenance
ReferencesPLoS ONE, 3(7):e2486 (2008). 18596935

Health Report

Examination Date / Room / Rack


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Ppme1protein phosphatase methylesterase 17Ppme1<tm1Crv>targeted mutation 1, Benjamin J Cravatt

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)7

Ordering Information

Donor DNAE. coli Neomycin resistnat gene, Mouse Ppme1 gene cDNA
Research application
Specific Term and ConditionsIn publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
DepositorBenjamin F. Cravatt (The Scripps Research Institute)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data