Strain Data Sheet


Strain Information

BRC No.RBRC11533
SpeciesMus musculus
Strain nameB6D2F1;B6-Ets2<em1Aitn>
Former Common nameEts2 em1
H-2 Haplotype
ES Cell line
Background strain
Strain developmentDeposited by Ayako Isotani, Nara Institute of Science and Technology in 2021. This strain was generated using fertilized eggs derived from (C57BL/6 x DBA/2)F1 x C57BL/6J. Mixed genetic background.
Strain descriptionCRISPR/Cas9 technology generated a 205 bp deletion in exon 8. Skin and thymus show a mutant mRNA lacking exon 8 and protein lacking exon 8 is detected in the thymus.
Colony maintenance
ReferencesSci. Rep., 11(1):8297 (2021) 33859300

Health Report

Examination Date / Room / Rack


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Ets2E26 avian leukemia oncogene 2, 3' domain16Ets2<em1Aitn>endonuclease-mediated mutation 1, Ayako Isotani

Ordering Information

Donor DNA
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Sci Rep. Apr 15;11(1):8297. (2021)For use of the BIOLOGICAL RESOURCE by a for-profit institution and an academic institution for the purpose of profits, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorAyako Isotani (Nara Institute of Science and Technology)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: CRISPR/Cas9 genome edited bioresources (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data