Strain Data Sheet



BRC No.RBRC11433
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129-Kdr<tm1.1Msh>
Former Common nameFLK1<1173F/+> mice、FLK1<1173F/1173F> mice
H-2 Haplotype
ES Cell lineE14 [129P2/OlaHsd]
Background strain
Strain developmentDeposited by Masabumi Shibuya, Jobu University in 2021. This strain was generated using E14 (ES Cell) derived from 129P2/OlaHsd. Mice were backcrossed to C57BL.6 for several generations. Mixed genetic background.
Strain descriptionKdr mutant harboring a point mutation (Y1173F) in the Kdr gene. A neo gene was deleted by CAG-Cre cross.
Colony maintenance
ReferencesProc. Natl. Acad. Sci. USA, 102, 1076-1081 (2005). 15644447

Health Report

Examination Date / Room / Rack


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Kdrkinase insert domain protein receptor5Kdr<tm1.1Msh>targeted mutation 1.1, Masabumi Shibuya

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP5loxP


Donor DNAP1 phage loxP, Mouse FLK1 gene: 変異Exon-27 (1173部位コドンの変異を含む)
Research applicationCre/loxP system
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Proc. Natl. Acad. Sci. USA., 102, 1076-1081 (2005).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
DepositorMasabumi Shibuya (Jobu University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data