Strain Data Sheet

RBRC11423

Strain Information

Image
BRC No.RBRC11423
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameB6-Tg(IVL-Cyp4f39)6Akih
Former Common nameCyp4f39 Tg
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeposited by Akio Kihara, Hokkaido University in 2021. C57BL/6 genetic background.
Strain descriptionTransgenic mice expressing Cyp4f39 under the control of the IVL promoter.
Colony maintenance
References
Lipid polarity gradient formed by omega-hydroxy lipids in tear film prevents dry eye disease.
Miyamoto M, Sassa T, Sawai M, Kihara A
eLife, 9:e53582 (2020). 32252890

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Cyp4f39 cytochrome P450, family 4, subfamily f, polypeptide 39UNCyp4f39 human IVL promoter
FLAG 3xFLAG tag (synthetic)UNFLAG
SV40 polyAUN

Phenotype

Phenotype annotation from literatures by Mammalian phenotype ontology
Detailed phenotype data

Ordering Information

Donor DNAhuman IVL promoter, SV40 splice donor seq, 3xFLAG tag, mouse Cyp4f39 cDNA, SV40 polyA signal
Research applicationMouse Models for Human Disease
Specific Term and ConditionsIn publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
DepositorAkio Kihara (Hokkaido University)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data