Strain Information | |
|---|---|
| Image | |
| BRC No. | RBRC11392 |
| Type | Targeted Mutation Congenic |
| Species | Mus musculus |
| Strain name | B6.Cg-Ebf1<tm1.1Tng> |
| Former Common name | Ebf1-flox |
| H-2 Haplotype | |
| ES Cell line | KY1.1[(C57BL/6J x 129S6/SvEvTac)F1] |
| Background strain | |
| Appearance | |
| Strain development | |
| Strain description | |
| Colony maintenance | |
| References | Stem cell niche-specific Ebf3 maintains the bone marrow cavity. Seike M, Omatsu Y, Watanabe H, Kondoh G, Nagasawa T Genes Dev., 32, 359-372 (2018). 29563184 |
Health Report | |
|---|---|
| Examination Date / Room / Rack | 2024/10/07Room:3-BRack:ISentinel mouse program 2024/04/08Room:3-BRack:ISentinel mouse program |
Gene | |||||||
|---|---|---|---|---|---|---|---|
| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| Ebf1 MGI:95275 | early B cell factor 1 | 11 | Ebf1<tm1.1Tng> | targeted mutation 1.1, Takashi Nagasawa | |||
| Frt | yeast FRT (flippase recombination target) site | 11 | Frt | ||||
| loxP | phage P1 loxP | 11 | loxP | ||||
Phenotype | |
|---|---|
| Phenotype annotation from literatures by Mammalian phenotype ontology | |
| Detailed phenotype data | |
Ordering Information | |
|---|---|
| Donor DNA | yeast FRT (flippase recombination target) site, phage P1 loxP sites, mouse Ebf1 genomic DNA |
| Research application | Cre/loxP system FLP/frt system |
| Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genes Dev., 32, 359-372 (2018). RECIPIENT which wants to use the BIOLOGICAL RESOURCE is requested to contact the depositor (Dr. Takashi Nagasawa) and enter into a Material Transfer Agreement with Osaka University. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. |
| Depositor | Takashi Nagasawa (Osaka University) |
| Strain Status | Frozen embryos Frozen sperm |
| Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
| Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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| No Data |