Strain Data Sheet



BRC No.RBRC11365
TypeTargeted Mutation CongenicCartagena
SpeciesMus musculus
Strain nameB6;Cg-Gad1<tm1.1(tTA2)Kftnk>
Former Common nameGad1-tTA knock-in mice
H-2 Haplotype
ES Cell line
Background strain
Strain developmentDeveloped by Yuchio Yanagawa, Gunma University, and Junichi Nakai, Tohoku University in 2006. Homozygous mice are neonatally lethal.
Strain descriptiontTA2 knockin mice at the Gad1 locus.
Colony maintenance
ReferencesCell Report 2, 397-406, 2012 22096083
Mol. Brain, 14(1):5 (2021). 33413507

Health Report

Examination Date / Room / Rack


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Gad1glutamate decarboxylase 12Gad1<tm1.1(tTA2)Kftnk>targeted mutation 1.1, Kenji Tanaka

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP2loxP

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
tTA2synthetic modified tetracycline-regulated transactivator2tTA2

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
SV40 polyA2


Donor DNA大腸菌およびヘルペスウイルス tTA2(テトラサイクリントランスアクチベーター2):大腸菌由来の the repressor of tetracycline resistance operonとヘルペスウイルスVP16 transcription avtivating domain(C末端の部分)との融合遺伝子(Urlinger et al., 2000), SV40ウイルス polyA, P1ファージ loxP
Research applicationCre/loxP system
Tet system
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Mol. Brain, 14(1):5 (2021). The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of not a not-for profit institution for a not-for-profit research.
DepositorYuchio Yanagawa (Gunma University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data