Strain Data Sheet

RBRC11352

Strain Information

Image
BRC No.RBRC11352
TypeCRISPR/Cas9Cartagena
SpeciesMus musculus
Strain nameB6-Clec7a<em1Yiw>
Former Common nameNew Dectin-1 KO/B6
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeposited by Yoichiro Iwakura, Tokyo University of Science, in 2022. Mice were generated using C57BL/6J with the CRISPR/Cas9. C57BL/6J genetic background.
Strain descriptionClec7a mutant mice. 5000bp deletion & 5bp replacement of the Clec7a gene.
Colony maintenance
References

Health Report

Examination Date / Room / Rack2025/08/18Room:3-6Rack:CSentinel mouse program
2025/06/09Room:3-6Rack:CSentinel mouse program
2025/03/10Room:3-6Rack:CSentinel mouse program
2024/12/09Room:3-6Rack:CSentinel mouse program
2024/09/09Room:3-6Rack:CSentinel mouse program
2024/06/10Room:3-6Rack:CSentinel mouse program
2024/03/11Room:3-6Rack:CSentinel mouse program

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Clec7a
MGI:1861431		C-type lectin domain family 7, member a6Clec7a<em1Yiw> endonuclease-mediated mutation 1, Yoichiro Iwakura
  • aspergillosis, susceptibility to(MedGEN)

  • candidiasis, familial, 4(MedGEN)

    • Phenotype

    Phenotype annotation from literatures by Mammalian phenotype ontology
    Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.
    DepositorYoichiro Iwakura (Tokyo University of Science)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: CRISPR/Cas9 genome edited bioresources (Japanese / English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data