Strain Data Sheet



BRC No.RBRC11342
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameEpac2 (Acc No. CDB0570K)
Former Common nameEpac2 (Acc No. CDB0570K)
H-2 Haplotype
ES Cell line
Background strain
Strain development
Strain description
Colony maintenance
ReferencesJ. Clin. Invest., 124(6):2785-801 (2014). 24892712

Health Report

Examination Date / Room / Rack


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Rapgef4Rap guanine nucleotide exchange factor (GEF) 42Rapgef4<tm1Yish>targeted mutation 1, Yoshihiro Ishikawa

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP2loxP

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)2mouse phosphoglycerate kinase promoter (PGK promoter)


Donor DNANeo:大腸菌由来、loxP:P1ファージ由来、PGKプロモーター,PGK 3’end:マウス由来
Research applicationCre/loxP system
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Clin. Invest., 124(6):2785-801 (2014).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The availability of the BIOLOGICAL RESOURCE is restricted to a RECIPIENT of a not-for organization for a not-for-profit research. The RECIPIENT shall obtain a prior agreement from the DEVELOPER(Yoshihiro Ishikawa to transfer the BIOLOGICAL RESOURCE. For use of the BIOLOGICAL RESOURCE by a for-profit organization or by a not-for profit organization for a for-profit research, the RECIPIENT must reach agreement on Terms and Conditions of use of it with the DEPOSITOR ( and must obtain a prior written consent from the DEPOSITOR. Please inform the DEPOSITOR about the paper when published.
DepositorHiroshi Kiyonari (RIKEN BDR)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data