Strain Data Sheet

RBRC11316

Information1

Image
BRC No.RBRC11316
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6-Oxt<tm1.1(Cre)Ksak>
Former Common nameOxt-iCre knock-in mice
H-2 Haplotype
ES Cell lineRENKA [C57BL/6NCrlCrlj]
Background strain
Appearance
Strain developmentDeposited by Teiichi Furuichi, Tokyo University of Science in 2021. Mice were generated using RENKA ES cells. C57BL/6 genetic background
Strain descriptionCre knock-in mice at exon3 of the Oxt gene.
Colony maintenance
ReferencesJ. Neurosci., 41(20):4524-4535 (2021). doi: 10.1523/JNEUROSCI.3240-20.2021. 33846232

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Oxtoxytocin2Oxt<tm1.1(cre)Ksak>targeted mutation 1.1, Kenji Sakimura

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
F2Afoot-and-mouth disease virus (FMD) 2A peptide2F2A

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Frtyeast FRT (flippase recombination target) site2Frt

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
icrephage P1 codon improved Cre (iCre)2icre

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
SV40 polyA2

Information2

Donor DNASaccharomyces cerevisiae FRT (flippase recombination target) site(J01347.1), Foot-and-mouth disease virus (FMDV derived) 2A peptide (F2A)(Coxsackievirus)(class 2), P1 Phage (class 1) iCre recombinase (YP_006472), SV40 (class 2) polyA, mouse Oxytocin (NM_011025.3)genomic DNA
Research applicationCre/loxP system
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J Neurosci. 2021 May 19;41(20):4524-4535. doi: 10.1523/JNEUROSCI.3240-20.2021.利用者は提供承諾書を用いて、事前に開発者(﨑村健司博士; sakimura@bri.niigata-u.ac.jp)の承諾を得る。
DepositorTeiichi furuichi (Tokyo University of Science)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data