Strain Data Sheet



BRC No.RBRC11286
SpeciesMus musculus
Strain nameC57BL/6J-Lta4h<em1Tyoko>
Former Common nameLTA4H-KO, Leukotriene A4 hydrolase KO mouse
H-2 Haplotype
ES Cell line
Background strain
Strain developmentDeposited by Takehiko Yokomizo, Juntendo University in 2021. C57BL/6J genetic background.
Strain descriptionLta4h mutant mice generated by the CRISPR/Cas9.
Colony maintenance
ReferencesCell Mol Immunol. Oct 9.(2020) doi: 10.1038/s41423-020-00559-7 33037399
FASEB J., 34(10):13949-13958 (2020). 32844470

Health Report

Examination Date / Room / Rack2022/08/29Room:4-CRack:J


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Lta4hleukotriene A4 hydrolase10Lta4h<em1Tyoko>


Donor DNA
Research applicationImmunology and Inflammation Research
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Cell Mol Immunol. 2020 Oct 9. doi: 10.1038/s41423-020-00559-7. FASEB J 34, 13949-13958 (2020).The RECIPIENT must contact the DEPOSITOR in the case of a application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorTakehiko Yokomizo (Juntendo University)
Strain Statusan icon for Live miceLive mice
an icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityCryopreserved sperm (within 1 month)
Live mouse (1 to 3 months)
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: CRISPR/Cas9 genome edited bioresources (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data