Strain Data Sheet



BRC No.RBRC11285
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6-Ltb4r1<tm1c(EUCOMM)Hmgu>/Tyoko
Former Common nameBLT1-KO, BLT1<flox/flox>
H-2 Haplotype
ES Cell line
Background strain
Strain developmentDeposited by Takehiko Yokomizo, Juntendo University in 2021. ES cells obtained from EUCOMM were used. Mice were further crossed with CAG-FLPe Tg mice to generate floxed allele. C57BL/6 genetic background.
Strain descriptionFloexed Ltb4r1 mice.
Colony maintenance
ReferencesJ. Clin. Invest., 128, p2691-2701 (2018). 29757196
Cell Mol Immunol. Oct 9(2020). doi: 10.1038/s41423-020-00559-7 33037399

Health Report

Examination Date / Room / Rack


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Ltb4r1leukotriene B4 receptor 114Ltb4r1<tm1c(EUCOMM)Hmgu>targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Frtyeast FRT (flippase recombination target) site14Frt

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP14loxP


Donor DNAバクテリオファージP1 loxP, Saccharomyces cerevisiae FRT
Research applicationCre/loxP system
FLP/frt system
Immunology and Inflammation Research
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Cell Mol Immunol. 2020 Oct 9. doi: 10.1038/s41423-020-00559-7. The RECIPIENT must contact the DEPOSITOR in the case of a application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. The RECIPIENT of RBRC11285 shall acknowledge the EUCOMM as the Provider of the ES cells to generate KO mice.
DepositorTakehiko Yokomizo (Juntendo University)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data