Strain Data Sheet



BRC No.RBRC11268
SpeciesMus musculus
Strain nameB6D2-Iqca<em1Osb>
Former Common nameIqca<-107633/wt>
H-2 Haplotype
ES Cell line
Background strain
Strain developmentDeposited by Masahito Ikawa, Research Institute for Microbial Diseases, Osaka University in 2020. Fertilized eggs derived from BDF1 × BDF1 were used to generate this line. Mixed genetic background.
Strain descriptionIqca knockout mouse generated by the CRISPR/Cas9. 107,633 bp deletion in the Iqca gene.
Colony maintenance
ReferencesBiol. Reprod., 103(2):183-194.(2020). doi: 10.1093/biolre/ioaa083. 32588039

Health Report

Examination Date / Room / Rack


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
IqcaIQ motif containing with AAA domain1Iqca<em1Osb>endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University


Donor DNAStreptococcus pyogenes crRNA, tracrRNA, Mouse a part of Iqca gene
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Biol Reprod. 2020 Aug 4;103(2):183-194. doi: 10.1093/biolre/ioaa083.RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University. The RECIPIENT which wants to use the BIOLOGICAL RESOURCE even after five years must obtain a written consent from the DEPOSITOR again.
DepositorMasahito Ikawa (Osaka University)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: CRISPR/Cas9 genome edited bioresources (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data