Strain Data Sheet

RBRC11194

Strain Information

Image
BRC No.RBRC11194
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6-Il2ra<tm1.1(DsRed)Shkm>
Former Common nameCD25<DsRed> knock-in mice
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeposited by Shigeo Koyasu in 2021. This strain was generated using B6JN/1 ES cells. The neo gene cassette was removed by crossing to B6;SJL-Tg(ACTFLPE)9205Dym/J.
Strain descriptionKnock-in mice in which DsRed (monomer) was placed at the CD25 gene locus.
Colony maintenance
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
SV40 polyA2
  • immunodeficiency due to CD25 deficiency(MedGEN)

  • type 1 diabetes mellitus 10(MedGEN)
    • DsRed MonomerRed Fluorescent Protein (Discosoma sp.)2DsRed Monomer
  • immunodeficiency due to CD25 deficiency(MedGEN)

  • type 1 diabetes mellitus 10(MedGEN)
    • Frtyeast FRT (flippase recombination target) site2Frt
  • immunodeficiency due to CD25 deficiency(MedGEN)

  • type 1 diabetes mellitus 10(MedGEN)
    • Il2rainterleukin 2 receptor, alpha chain2Il2ratargeted mutation 1.1, Shigeo Koyasu
  • immunodeficiency due to CD25 deficiency(MedGEN)

  • type 1 diabetes mellitus 10(MedGEN)

    • Phenotype

    Annotation by Mammalian phenotyhpe ontology
    Detailed phenotype data

    Ordering Information

    Donor DNADiscosoma spp. DsRed Monomer cDNA, Saccharomyces cerevisiae Flp recombination target site (FRT), Simian virus 40 (SV40) polyA signal
    Research applicationFLP/frt system
    Fluorescent Proteins/lacZ System
    Specific Term and ConditionsIn publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
    DepositorShigeo Koyasu (RIKEN)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovery and QC required prior to distribution
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: FP license of TBUSA
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    BRC mice in Publications

    No Data