Strain Data Sheet
RBRC11174
Strain Information | |
|---|---|
| Image | |
| BRC No. | RBRC11174 |
| Type | Transgene |
| Species | Mus musculus |
| Strain name | C57BL/6J-Tg(mCNE-mhsp68-mEvi1)1Kmori |
| Former Common name | Evi1-Tg |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | |
| Appearance | |
| Strain development | Deposited by Kazuhiro Morishita, Miyazaki University in 2020. C57BL/6J genetic background. |
| Strain description | Transgenic mice expressing mouse Evi1 under the control of chimeric promoter, Runx1+24 mouse conserved noncoding element (mCNE) and mouse heatshock protein 68 minimal promoter. |
| Colony maintenance | |
| References | EVI1 triggers metabolic reprogramming associated with leukemogenesis and increases sensitivity to L-asparaginase. Saito Y, Sawa D, Kinoshita M, Yamada A, Kamimura S, Suekane A, Ogoh H, Matsuo H, Adachi S, Taga T, Tomizawa D, Osato M, Soga T, Morishita K, Moritake H Haematologica, 105(8):2118-2129 (2020). doi: 10.3324/haematol.2019.225953. 31649131 |
Health Report | |
|---|---|
| Examination Date / Room / Rack | |
Gene | |||||||
|---|---|---|---|---|---|---|---|
| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| SV40 polyA | UN | ||||||
| Mecom | MDS1 and EVI1 complex locus | UN | Mecom | mouse Runx1 enhancer, mouse hsp68 promoter | |||
Phenotype | |
|---|---|
| Annotation by Mammalian phenotyhpe ontology | |
| Detailed phenotype data | |
Ordering Information | |
|---|---|
| Donor DNA | mouse Runx1 enhancer, mouse hsp68 promoter, Mouse Evi1 cDNA, SV40 virus polyA |
| Research application | Hematological Research |
| Specific Term and Conditions | For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. |
| Depositor | Kazuhiro Morishita (University of Miyazaki) |
| Strain Status |  Frozen sperm |
| Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
| Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
|---|
| No Data |