Strain Data Sheet

RBRC11159

Strain Information

Image
BRC No.RBRC11159
TypeRecombinant Congenic
SpeciesMus musculus
Strain nameMcH/Mo-Ank.Y<MRL>
Former Common nameMcH-Ank.Y<MRL>
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeposited by Tetsuya Kodama, Tohoku University in 2020.
Strain description
Colony maintenance
References
Genetic characterisation of spontaneous ankylosing arthropathy with unique inheritance from Fas-deficient strains of mice.
Mori S, Zhang M C, Tanda N, Date F, Nose M, Furukawa H, Ono M
Ann. Rheum. Dis., 65(10):1273-8 (2006). 16569686

A signal adaptor SLAM-associated protein regulates spontaneous autoimmunity and Fas-dependent lymphoproliferation in MRL-Faslpr lupus mice.
Komori H, Furukawa H, Mori S, Ito M R, Terada M, Zhang M C, Ishii N, Sakuma N, Nose M, Ono M
J. Immunol., 176(1):395-400 (2006). 16365433

A non-major histocompatibility locus determines tissue specificity in the pathogenic process underlying synovial proliferation in a mouse arthropathy model.
Zhang M C, Mori S, Date F, Furukawa H, Ono M
Ann. Rheum. Dis., 66(2):242-5 (2007). 16868019

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Fas
MGI:95484		Fas cell surface death receptor19Fas<lpr>
MGI:1856334		lymphoproliferation
  • autoimmune lymphoproliferative syndrome type 1(DisGeNET, MedGEN)

    • Phenotype

    Phenotype annotation from literatures by Mammalian phenotype ontology
    Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Immunol., 176(1):395-400 (2006). Ann. Rheum. Dis., 65(10):1273-8 (2006).
    DepositorTetsuya Kodama (Tohoku University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    BRC mice in Publications

    No Data