Strain Data Sheet
RBRC11106
Strain Information | |
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| Image | |
| BRC No. | RBRC11106 |
| Type | Targeted Mutation |
| Species | Mus musculus |
| Strain name | C.B6-C1qtnf3<tm1Yiw> |
| Former Common name | CTRP3 KO/BALB |
| H-2 Haplotype | |
| ES Cell line | EGR-101 [C57BL/6N] |
| Background strain | |
| Appearance | |
| Strain development | Deposited by Yoichiro Iwakura, Tokyo University of Science, in 2020. Mice were generated using EGR-101 ES cells derived from C57BL/6N. Mice were further backcrossed to BALB/c for 6 generations. BALB/c congenic strain. |
| Strain description | C1qtnf3 knockout mice. A floxed neomycin resistance cassette replaced exon 4 of the C1qtnf3 gene. |
| Colony maintenance | |
| References | CTRP3 plays an important role in the development of collagen-induced arthritis in mice. Murayama M A, Kakuta S, Maruhashi T, Shimizu K, Seno A, Kubo S, Sato N, Saijo S, Hattori M, Iwakura Y Biochem. Biophys. Res. Commun., 443, 42-48 (2014). 24269820 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |||||||
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| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| C1qtnf3 | C1q and tumor necrosis factor related protein 3 | 15 | C1qtnf3 | targeted mutation 1, Yoichiro Iwakura | |||
| GH | Growth hormone polyA (Bovine) | 15 | GH | ||||
| loxP | phage P1 loxP | 15 | loxP | ||||
| loxP | phage P1 loxP | 15 | loxP | ||||
| neo | neomycin resistance gene (E. coli) | 15 | mouse phosphoglycerate kinase promoter (PGK promoter) | ||||
Phenotype | |
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| Annotation by Mammalian phenotyhpe ontology | |
| Detailed phenotype data | |
Ordering Information | |
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| Donor DNA | E.coli Neomycin resistant gene, mouse Phosphoglycerate kinase (PGK) promoter, P1 Phage loxP, Bovine growth hormone polyadenylation site |
| Research application | Cre/loxP system |
| Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. |
| Depositor | Yoichiro Iwakura (Tokyo University of Science) |
| Strain Status |  Frozen embryos |
| Strain Availability |  Recovery and QC required prior to distribution |
| Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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| No Data |