Strain Information | |
---|---|
Image | |
BRC No. | RBRC11105 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6-C1qtnf3<tm1Yiw> |
Former Common name | CTRP3 KO/B6 |
H-2 Haplotype | |
ES Cell line | EGR-101 [C57BL/6N] |
Background strain | |
Appearance | |
Strain development | Deposited by Yoichiro Iwakura, Tokyo University of Science, in 2020. Mice were generated using EGR-101 ES cells derived from C57BL/6N. C57BL/6 genetic background. |
Strain description | C1qtnf3 knockout mice. A floxed neomycin resistance cassette replaced exon 4 of the C1qtnf3 gene. |
Colony maintenance | |
References | CTRP3 plays an important role in the development of collagen-induced arthritis in mice. Murayama M A, Kakuta S, Maruhashi T, Shimizu K, Seno A, Kubo S, Sato N, Saijo S, Hattori M, Iwakura Y Biochem. Biophys. Res. Commun., 443, 42-48 (2014). 24269820 |
Health Report | |
---|---|
Examination Date / Room / Rack |
Gene | |||||||
---|---|---|---|---|---|---|---|
Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
C1qtnf3 | C1q and tumor necrosis factor related protein 3 | 15 | C1qtnf3 | targeted mutation 1, Yoichiro Iwakura | |||
GH | Growth hormone polyA (Bovine) | 15 | GH | ||||
loxP | phage P1 loxP | 15 | loxP | ||||
loxP | phage P1 loxP | 15 | loxP | ||||
neo | neomycin resistance gene (E. coli) | 15 | mouse phosphoglycerate kinase promoter (PGK promoter) |
Phenotype | |
---|---|
Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
---|---|
Donor DNA | E.coli Neomycin resistant gene, mouse Phosphoglycerate kinase (PGK) promoter, P1 Phage loxP, Bovine growth hormone polyadenylation site |
Research application | Cre/loxP system |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. |
Depositor | Yoichiro Iwakura (Tokyo University of Science) |
Strain Status | Frozen embryos |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
---|
No Data |