Strain Data Sheet

RBRC11105

Strain Information

Image
BRC No.RBRC11105
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6-C1qtnf3<tm1Yiw>
Former Common nameCTRP3 KO/B6
H-2 Haplotype
ES Cell lineEGR-101 [C57BL/6N]
Background strain
Appearance
Strain developmentDeposited by Yoichiro Iwakura, Tokyo University of Science, in 2020. Mice were generated using EGR-101 ES cells derived from C57BL/6N. C57BL/6 genetic background.
Strain descriptionC1qtnf3 knockout mice. A floxed neomycin resistance cassette replaced exon 4 of the C1qtnf3 gene.
Colony maintenance
References
CTRP3 plays an important role in the development of collagen-induced arthritis in mice.
Murayama M A, Kakuta S, Maruhashi T, Shimizu K, Seno A, Kubo S, Sato N, Saijo S, Hattori M, Iwakura Y
Biochem. Biophys. Res. Commun., 443, 42-48 (2014). 24269820

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
C1qtnf3
MGI:1932136		C1q and tumor necrosis factor related protein 315C1qtnf3<tm1Yiw> targeted mutation 1, Yoichiro Iwakura
GH Growth hormone polyA (Bovine)15GH
loxP phage P1 loxP15loxP
loxP phage P1 loxP15loxP
neo neomycin resistance gene (E. coli)15 mouse phosphoglycerate kinase promoter (PGK promoter)

Phenotype

Phenotype annotation from literatures by Mammalian phenotype ontology
Detailed phenotype data

Ordering Information

Donor DNAE.coli Neomycin resistant gene, mouse Phosphoglycerate kinase (PGK) promoter, P1 Phage loxP, Bovine growth hormone polyadenylation site
Research applicationCre/loxP system
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.
DepositorYoichiro Iwakura (Tokyo University of Science)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data