Strain Data Sheet

RBRC11101

Strain Information

Image
BRC No.RBRC11101
TypeCRISPR/Cas9Cartagena
SpeciesMus musculus
Strain nameC57BL/6J-Slc27a4<em1Akih>
Former Common nameSlc27a4/Fatp4 KO
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeposited by Akio Khara in 2020. Mice were generated using C57BL/6J with the CRISPR/Cas9. C57BL/6J genetic background.
Strain descriptionSlc27a4 mutant mice. 1 bp insertion at exon 3 of the Slc27a4 gene.
Colony maintenance
References
Skin permeability barrier formation by the ichthyosis-causative gene FATP4 through formation of the barrier lipid omega-O-acylceramide.
Yamamoto H, Hattori M, Chamulitrat W, Ohno Y, Kihara A
Proc. Natl. Acad. Sci. USA, 117, 2914-2922 (2020). 31974308

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Slc27a4
MGI:1347347		solute carrier family 27 (fatty acid transporter), member 42Slc27a4<em1Akih> endonuclease-mediated mutation 1, Akio Kihara
  • ichthyosis prematurity syndrome(MedGEN)

    • Phenotype

    Phenotype annotation from literatures by Mammalian phenotype ontology
    Detailed phenotype data

    Ordering Information

    Donor DNA
    Research applicationDermatology Research
    Mouse Models for Human Disease
    Specific Term and ConditionsIn publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
    DepositorAkio Kihara (Hokkaido University)
    Strain Statusan icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: CRISPR/Cas9 genome edited bioresources (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    BRC mice in Publications

    No Data