Strain Data Sheet
RBRC10981
Strain Information | |
|---|---|
| Image | |
| BRC No. | RBRC10981 |
| Type | Targeted Mutation |
| Species | Mus musculus |
| Strain name | B6.129-Tigar<tm1.2Smat> |
| Former Common name | TIGAR(-/-) mice |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | |
| Appearance | |
| Strain development | |
| Strain description | |
| Colony maintenance | |
| References | p53-TIGAR axis attenuates mitophagy to exacerbate cardiac damage after ischemia. Hoshino A, Matoba S, Iwai-Kanai E, Nakamura H, Kimata M, Nakaoka M, Katamura M, Okawa Y, Ariyoshi M, Mita Y, Ikeda K, Ueyama T, Okigaki M, Matsubara H J. Mol. Cell. Cardiol., 52 (1)175-184 (2012). 22044588 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |||||||
|---|---|---|---|---|---|---|---|
| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| Frt | yeast FRT (flippase recombination target) site | 6 | Frt | ||||
| Tigar MGI:2442752 | Trp53 induced glycolysis regulatory phosphatase | 6 | Tigar<tm1.2Smat> | targeted mutation 1.2, Satoaki Matoba | |||
| loxP | phage P1 loxP | 6 | loxP | ||||
Phenotype | |
|---|---|
| Annotation by Mammalian phenotyhpe ontology | |
| Detailed phenotype data | |
Ordering Information | |
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| Donor DNA | マウス TIGAR 遺伝子 , P1 phage loxP, yeast FRT |
| Research application | Cardiovascular Research Cre/loxP system FLP/frt system |
| Specific Term and Conditions | In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. |
| Depositor | Satoaki Matoba (Kyoto Prefectural University of Medicine) |
| Strain Status |  Frozen sperm |
| Strain Availability |  Recovery and QC required prior to distribution |
| Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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| No Data |