Strain Data Sheet
RBRC10971
Information1 | |
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| Image | |
| BRC No. | RBRC10971 |
| Type | Targeted Mutation Congenic |
| Species | Mus musculus |
| Strain name | B6.Cg-Serpinh1<tm1Kzn> |
| Former Common name | Hsp47 +/- |
| H-2 Haplotype | |
| ES Cell line | E14 [129P2/OlaHsd] |
| Background strain | |
| Appearance | |
| Strain development | Developed by Kazuhiro Nagata, Kyoto University in 2000. E14 ES cells derived from 129P2/OlaHsd were used. C57BL/6 congenic strain by backcrossing over 21 generations. |
| Strain description | Serpinh1 (Hsp47) knockout mice. Exon 4 was replaced with the Neo gene cassette. |
| Colony maintenance | |
| References | J. Cell Biol. 150(6):1499-506 (2000). 10995453 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |
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| Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Serpinh1serine (or cysteine) peptidase inhibitor, clade H, member 17Serpinh1<tm1Kzn>targeted mutation 1, Kazuhiro Nagata Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)7herpes simplex virus thymidine kinase promoter (HSV tk promoter) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter SV40 polyA signal7 |
Information2 | |
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| Donor DNA | Herpes Simplex virus (HSV) Thymidine kinase (TK) promoter, E. coli Neomycin resistant gene, SV40 polyA signal, mouse Serpinh1 genomic DNA |
| Research application | |
| Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Cell Biol. 150(6):1499-506 (2000).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
| Depositor | Kazuhiro Nagata (Kyoto Sangyo University) |
| Strain Status |  Frozen embryos |
| Strain Availability |  Recovery and QC required prior to distribution |
| Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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