Strain Data Sheet


Strain Information

BRC No.RBRC10950
SpeciesMus musculus
Strain nameC57BL/6-Tg(CAG-Sphk1)H1Ytak
Former Common nameSphk1 transgenic mice (Tg line: High)
H-2 Haplotype
ES Cell line
Background strain
Strain developmentDeveloped by Yo Takuwa, Kanazawa University in 2003. C57BL/6 genetic background.
Strain descriptionTransgenic mice expressing mouse Sphk1 gene cDNA under the control of CAG promoter.
Colony maintenance
ReferencesCardiovasc. Res., 85(3):484-93 (2010). 19755413
Cardiovasc. Res., 78, 301-307 (2008). 18187460
Diabetes, 61, 3148-3155 (2012). 22961081

Health Report

Examination Date / Room / Rack


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Sphk1sphingosine kinase 1UNSphk1CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA)

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
SV40 polyA signalUN

Ordering Information

Donor DNACytomegalovirus CMV-IE enhancer, Chicken beta-actin promoter, Rabbit beta-globin genomic DNA, Mouse Sphk1a gene cDNA, SV40 PolyA signal
Research application
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Cardiovasc Res. 2010 Feb 1;85(3):484-93. doi: 10.1093/cvr/cvp312
DepositorYoh Takuwa (Kanazawa University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  4. CAGGS MTA (English)
  5. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data