Strain Data Sheet
RBRC10923
Strain Information | |
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| Image | |
| BRC No. | RBRC10923 |
| Type | Transgene |
| Species | Mus musculus |
| Strain name | B6.B6D2-Tg(Krt19-icre)2Hirt |
| Former Common name | Krt19 iCre |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | |
| Appearance | |
| Strain development | Deposited by Hiroyuki Tomita, Gifu University in 2019. A BAC transgenic DNA was injected to fertilized eggs derived from BDF mice. Mice were further backcrossed to C57B6/J for 10 generations. C57B6/J congenic strain. |
| Strain description | BAC transgenic mice expressing iCre under the control of Krt19 gene promoter. |
| Colony maintenance | |
| References | Characterization of a BAC transgenic mouse expressing Krt19-driven iCre recombinase in its digestive organs. Kanayama T, Tomita H, Binh N H, Hatano Y, Aoki H, Okada H, Hirata A, Fujihara Y, Kunisada T, Hara A PLoS One, 14(8):e0220818 (2019). 31393940 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |||||||
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| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| Frt | yeast FRT (flippase recombination target) site | UN | Frt | ||||
| icre | phage P1 codon improved Cre (iCre) | UN | icre | mouse Krt19 promoter | |||
| Simian virus SV40 polyA | UN | ||||||
Phenotype | |
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| Phenotype annotation from literatures by Mammalian phenotype ontology | |
| Detailed phenotype data | |
Ordering Information | |
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| Donor DNA | mouse Krt19 genomic DNA, phage P1 iCre (improved Cre), yeast FRT (flippase recombination target) site, Simian virus SV40 polyA |
| Research application | Cre/loxP system FLP/frt system Cre driver |
| Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. PLoS One, 14(8):e0220818 (2019). |
| Depositor | Hiroyuki Tomita (Gifu University) |
| Strain Status |  Frozen embryos Frozen sperm |
| Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
| Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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| No Data |