Strain Data Sheet

RBRC10904

Information1

Image
BRC No.RBRC10904
TypeTransgeneCartagena
SpeciesMus musculus
Strain name129.Cg-Tg(Th-MYCN)41WawKkad
Former Common nameTh-MYCN, TH-MYCN
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeposited by Welliam A. Weiss in 2020.
Strain descriptionThe rat tyrosine hydrolase promoter directs expression of human v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) (MYCN) to migrating cells of the neural crest during early development.
Colony maintenance
ReferencesEMBO J., 16(11):2985-95 (1997). 9214616

Health Report

Examination Date / Room / Rack2022/08/29Room:4-CRack:K
2022/05/31Room:4-CRack:K
2022/03/15Room:4-CRack:K
2021/12/13Room:4-CRack:K
2021/09/13Room:4-CRack:K

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
HBB2rabbit beta-globin Intron (enhancer)UNHBB2

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
MYCNHuman MYCN cDNAUNMYCNrat tyrosine hydroxylase (TH) promoter

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Herpes simplex virus Thymidine kinase gene terminator/poly(A) sequenceUN

Information2

Donor DNARat Tyrosine Hydroxylase Promoter, Rabbit Beta-Globin Intron (enhancer), Human MYCN cDNA, Herpes simplex virus Thymidine kinase gene terminator/poly(A) sequence
Research applicationCancer Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. EMBO J. 1997 Jun 2;16(11):2985-95Limitation of recipients of the BIOLOGICAL RESOURCE to not-for-profit institutions, limitation of the use to academic research purposes for-profit institutions or use for commercial research purposesshall acquire a prior written consent from the Depositor.
DepositorWilliam Weiss (The University of California, San Francisco)
Strain Statusan icon for Live miceLive mice
an icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityCryopreserved embryos (within 1 month)
Live mouse (1 to 3 months)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data