Information1 | |
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Image | |
BRC No. | RBRC10844 |
Type | Targeted Mutation Congenic![]() |
Species | Mus musculus |
Strain name | B6.Cg-Rit1<tm1.1(A57G)Tumg> |
Former Common name | Rit1A57G/+ (Rit1 A57G knock-in mice; C57BL/6J background) |
H-2 Haplotype | |
ES Cell line | Bruce 4 [B6.Cg-Thy1<a>] |
Background strain | |
Appearance | |
Strain development | Developed by Yoko Aoki and Shin-ichi Inoue, Tohoku University School of Medicine in 2019. BRUCE-4 ES cells were used. C57BL/6 congenic line. |
Strain description | Knock-in mutants in which a point mutation (A57G) was introduced at Exon 4 of the Rit1 gene. Floxed stop cassette and Frt-flnaked Neo cassette at intron 3 were removed by crossing with Cre mice. |
Colony maintenance | |
References | EBioMedicine, 42:43-53 (2019). 30898653 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP3loxP |
Information2 | |
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Donor DNA | Bacteriophage P1 loxP site, mouse Rit1 genomic DNA |
Research application | Cre/loxP system |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. EBioMedicine, 42:43-53 (2019).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Yoko Aoki (Tohoku University) |
Strain Status | ![]() ![]() |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |