Strain Data Sheet

RBRC10789

Information1

Image
BRC No.RBRC10789
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6N-Ttr<tm1.1(NLS/cre)Card>
Former Common nameTtr-Cre
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Michihiko Sugimoto and Kimi Araki at Card, Kumamoto University in 2017. 6NK-7 ES cells derived from C57BL/6N were used to generate this strain. C57BL/6N genetic background.
Strain descriptionKnockin mice in which NLS-Cre replaced the coding sequence for the Ttr gene.
Colony maintenance
References本系統を用いて公表された第一報の論文

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Ttrtransthyretin18Ttr<tm1.1(NLS/cre)Card>targeted mutation 1.1, Center for Animal Resources & Development

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
En2En2 SA (mouse En2 intron 2/exon 3 splice acceptor sequence)18En2

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
HBB2rabbit beta-globin intron18HBB2

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
crePhage P1 Cre recombinase18cre

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP18loxP

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
nlsSV40 large T antigen nuclear localization signal (NLS)18nls

Information2

Donor DNASV40 large T antigen nuclear localization signal (NLS), Rabbit beta-globin intron, mouse En-2 intron/exron splicing acceptor, Phage P1 Cre, mouse Pgk polyA signal, Phage P1 loxP site, mouse Ttr genomic DNA
Research applicationCre/loxP system
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. 本系統を用いて公表された第一報の論文In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent form the DEPOSITOR.
DepositorKimi Araki (Kumamoto University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data