Strain Information | |
|---|---|
| Image | |
| BRC No. | RBRC10705 |
| Type | Transgene |
| Species | Mus musculus |
| Strain name | C57BL/6J-Tg(S100b-cre)20Ito |
| Former Common name | S100b-Cre |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | |
| Appearance | |
| Strain development | Deposited by Shigeyoshi Itohara, RIKEN Center for Brain Science. C57BL/6 genetic background. |
| Strain description | Transgenic mice expressing Cre under the control of S100b promoter. |
| Colony maintenance | |
| References | Connexin43 and bergmann glial gap junctions in cerebellar function. Tanaka M, Yamaguchi K, Tatsukawa T, Theis M, Willecke K, Itohara S Front. Neurosci., 2(2):225-33 (2008). 19225596Lack of Connexin43-mediated bergmann glial gap junctional coupling does not affect cerebellar long-term depression, motor coordination, or eyeblink conditioning. Tanaka M, Yamaguchi K, Tatsukawa T, Nishioka C, Nishiyama H, Theis M, Willecke K, Itohara S Front. Behav. Neurosci., 2:1 (2008). 18958191 |
Health Report | |
|---|---|
| Examination Date / Room / Rack | |
Gene | |||||||
|---|---|---|---|---|---|---|---|
| Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
| cre | Phage P1 Cre recombinase | UN | cre | ||||
| nls | SV40 large T antigen nuclear localization signal (NLS) | UN | nls | ||||
| HSV TK polyA | UN | ||||||
Phenotype | |
|---|---|
| Phenotype annotation from literatures by Mammalian phenotype ontology | |
| Detailed phenotype data | |
Ordering Information | |
|---|---|
| Donor DNA | mouse S100b genomic DNA, SV40 large T antigen nuclear localization signal (NLS), Phage P1 Cre recombinase, E. coli neo (partial sequence), HSV tk polyA |
| Research application | Cre/loxP system Cre driver |
| Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Front. Neurosci., 2(2):225-33 (2008). Front. Behav. Neurosci., 2:1 (2008). |
| Depositor | Shigeyoshi Itohara (RIKEN) |
| Strain Status | Frozen embryos Frozen sperm |
| Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) |
| Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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| No Data |