Strain Data Sheet

RBRC10695

Strain Information

Image
BRC No.RBRC10695
TypeCRISPR/Cas9Cartagena
SpeciesMus musculus
Strain nameC57BL/6J-Prkdc<em1Nsas>
Former Common nameB6-Prkdc KO
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Nobuya Sasaki and Tadashi Okamura in 2018 with the CRISPR/Cas9 technique. C57BL/6JJcl genetic background.
Strain descriptionPrkdc deficient mice in C57BL/6JJcl genetic background.
Colony maintenance
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Prkdcprotein kinase, DNA activated, catalytic polypeptide16Prkdcendonuclease-mediated mutation 1, Nobuya Sasaki
  • severe combined immunodeficiency due to DNA-PKcs deficiency(MedGEN)

    • Phenotype

    Annotation by Mammalian phenotyhpe ontology
    Detailed phenotype data

    Ordering Information

    Donor DNAmouse Prkdc
    Research application
    Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. Depending on the content of the research, the DEPOSITOR may request collaboration.
    DepositorNobuya Sasaki (Kitasato University)
    Strain Statusan icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: CRISPR/Cas9 genome edited bioresources (Japanese / English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data