Strain Data Sheet

RBRC10624

Strain Information

Image
BRC No.RBRC10624
TypeTargeted Mutation CongenicCartagena
SpeciesMus musculus
Strain nameB6.Cg-Tlk2<tm1.1Chum>
Former Common nameTlk2 gene targeted knockout
H-2 Haplotype
ES Cell lineKY1.1[(C57BL/6J x 129S6/SvEvTac)F1]
Background strain
Appearance
Strain developmentDeveloped by Shinichiro Chuma, Institute for Frontier Life and Medical Sciences, Kyoto University in 2019. KY1.1 ES cells derived from (C57BL/6J x 129S6/SvEvTac)F1 were used. The strain was backcrossed to C57BL/6J for 11 generations.
Strain descriptionTlk2 knockout mice. Exon 14 to Exon 16 were deleted.
Colony maintenance
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Tlk2tousled-like kinase 2 (Arabidopsis)11Tlk2targeted mutation 1.1, Shinichiro Chuma
  • intellectual disability, autosomal dominant 57(MedGEN)
    • loxPphage P1 loxP11loxP
  • intellectual disability, autosomal dominant 57(MedGEN)

    • Phenotype

    Annotation by Mammalian phenotyhpe ontology
    Detailed phenotype data

    Ordering Information

    Donor DNAP1 Phage loxP site, mouse Tlk2 genomic DNA
    Research applicationCre/loxP system
    Specific Term and Conditions・ Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval form the
    DEVELOPER (Dr. Shinichiro Chuma) using the Approval Form.
    ・ The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a non-for profit
    organization for a research and academic research purpose.
    DepositorShinichiro Chuma (Kyoto University)
    Strain Statusan icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data