Strain Data Sheet

RBRC10608

Information1

Image
BRC No.RBRC10608
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6-Chn1<tm3.2Ito>
Former Common nameChn1 (alpha1 isoform) knockout
H-2 Haplotype
ES Cell lineMS12 [C57BL/6]
Background strain
Appearance
Strain developmentDeposited by Shigeyoshi Itohara, RIKEN Center for Brain Science. MS12 ES cells derived from C57BL6, and then mice were crossed to C57BL/6J.
Strain descriptionα1 chimaerin (chimerin) knockout mice. Exon 7 of the Chn1 gene containing transcription initiation site for α1 chimaerin (chimerin) was deleted.
Colony maintenance
ReferencesCell Rep., 8(5) 1257-1264 (2014). 25159148

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Chn1chimerin 12Chn1<tm3.2Ito>targeted mutation 3.2, Shigeyoshi Itohara

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Frtyeast FRT (flippase recombination target) site2Frt

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP2loxP

Information2

Donor DNAP1ファージ LoxP配列, マウス Chn1
Research applicationCre/loxP system
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Cell Rep. 2014 Sep 11;8(5):1257- 64. doi: 10.1016/ j.celrep.2014.07.047. Epub 2014 Aug 21In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
DepositorShigeyoshi Itohara (RIKEN)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data