Strain Data Sheet



BRC No.RBRC10605
TypeSpontaneous Mutation
SpeciesMus musculus
Strain nameC57BL/6-Chn1<mfy>/Ito
Former Common namemiffy
H-2 Haplotype
ES Cell line
Background strain
Strain developmentDeposited by Shigeyoshi Itohara, RIKEN Center for Brain Science. Ryosuke Takahashi and Haruhisa Inoue found miffy mutants. Takuji Iwasato and Shigeyoshi Itohara identified causal gene.
Strain descriptionmiffy spontaneous mutant. A retroposon insertion at exon 9 of the Chn1 (chimerin 1), which resulted in loss of Rac-GAP activity and caused locomotor activity deficit.
Colony maintenance
ReferencesCell, 130 (4), 742-753 (2007). 17719550

Health Report

Examination Date / Room / Rack


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Chn1chimerin 12Chn1<mfy>miffy


Donor DNA
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Cell. Volume 130 , Issue 4, 24 August 2007, Pages 742-753In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
DepositorShigeyoshi Itohara (RIKEN)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

BRC mice in Publications

No Data