Strain Information | |
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Image | |
BRC No. | RBRC10588 |
Type | CRISPR/Cas9 |
Species | Mus musculus |
Strain name | C57BL/6-Pnldc1<em2Nkn> |
Former Common name | Pnldcl_Exon 7-mut, Pnldc1-mut |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Toru Nakano, Graduate School of Frontier Biosciences, Osaka University. C57BL/6 genetic background. |
Strain description | Pnldc1 (poly(A)-specific ribonuclease (PARN)-like domain containing 1) mutant mice. 836 bp insertion at Exon 7 generated with the Crispr/Cas9 technique and fertilized eggs derived from C57BL/6. Homozygous males are infertile, whereas homozygous females are fertile. |
Colony maintenance | |
References | EMBO Rep. 2018 Mar;19(3). pii: e44957. doi: 10.15252/embr.201744957. 29444933 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Pnldc1poly(A)-specific ribonuclease (PARN)-like domain containing 117Pnldc1<em2Nkn>endonuclease-mediated mutation 2, Toru Nakano |
Ordering Information | |
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Donor DNA | マウス Pnldc1 |
Research application | |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. EMBO Rep., 19(3) pii: e44957 (2018).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University. |
Depositor | Toru Nakano (Osaka University) |
Strain Status | Frozen embryos |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |