|Former Common name
|ES Cell line
|Developed by Toru Nakano, Graduate School of Frontier Biosciences, Osaka University. C57BL/6 genetic background.
|Pnldc1 (poly(A)-specific ribonuclease (PARN)-like domain containing 1) mutant mice. 11 bp deletion at Exon 3 generated with the Crispr/Cas9 technique and fertilized eggs derived from C57BL/6. Homozygous males are infertile, whereas homozygous females are fertile.
|EMBO Rep. 2018 Mar;19(3). pii: e44957. doi: 10.15252/embr.201744957. 29444933
|Examination Date / Room / Rack
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
|Specific Term and Conditions
|In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Nishimura T, Nagamori I, Nakatani T, Izumi N, Tomari Y, Kuramochi-Miyagawa S, Nakano T. PNLDCl, mouse pre-piRNA Trimmer, is required for meiotic and post-meiotic male germ cell development. EMBO Rep. 2018 Mar;l9(3). pii: e44957. doi: 10.15252/embr.201744957.In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University.
|Toru Nakano (Osaka University)
|Recovery and QC required prior to distribution
|Necessary documents for ordering:
BRC mice in Publications