Strain Data Sheet

RBRC10580

Strain Information

Image
BRC No.RBRC10580
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6N-Adrm1<tm1.1Smta>
Former Common nameRpnl3KO
H-2 Haplotype
ES Cell lineRENKA [C57BL/6NCrlCrlj]
Background strain
Appearance
Strain developmentDeveloped by Jun Hamazaki, The University of Tokyo in 2009. f
Strain descriptionAdrm1 (adhesion regulating molecule 1, Rpn13 Rpn13) knockout mice. Exon 3 and 4 of the Adrm1 gene are deleted. Homozygous mutants are neonatally lethal.
Colony maintenance
References
Redundant Roles of Rpn10 and Rpn13 in Recognition of Ubiquitinated Proteins and Cellular Homeostasis.
Hamazaki J, Hirayama S, Murata S
PLoS Genet. 2015 Jul 29;11(7):e1005401 26222436

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Adrm1adhesion regulating molecule 1 26S proteasome ubiquitin receptor2Adrm1targeted mutation 1.1, Shigeo Murata
loxPphage P1 loxP2loxP

Phenotype

Annotation by Mammalian phenotyhpe ontology
Detailed phenotype data

Ordering Information

Donor DNAPhage P1 1oxP site, mouse Adrm1 genomic DNA
Research applicationCre/loxP system
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Hamazaki J, Hirayama S, Murata S. (2015) Redundant roles of Rpn10 and Rpnl3 in recognition of ubiquitinated proteins and cellular homeostasis . PLoS Genet.In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
DepositorShigeo Murata (The University of Tokyo)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data