BRC No.RBRC10482
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6-Pkm<tm3Ntan>
Former Common namePkmM2
H-2 Haplotype
ES Cell lineRENKA [C57BL/6NCrlCrlj]
Background strain
Strain development
Strain description
Colony maintenance
ReferencesCancer Cell, 33(3): 355-367 (2018). 29533781

Health Report

Examination Date / Room / RackNo Data


Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Pkmpyruvate kinase, muscle9Pkm<tm3Ntan>

Gene symbolGene nameChr.Allele symbolAllele namePromoter

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)9mouse phosphoglycerate kinase promoter (PGK promoter)

Gene symbolGene nameChr.Allele symbolAllele namePromoter
SV40 polyA signal9


Donor DNAhuman PKM1 cDNA, SV40 polyA additional signal, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli Neomycin resistance gene, mouse Pkm genomic DNA
Research applicationCancer Research
Metabolism Research
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Mami Morita et al., Cancer Cell, 33(3): 355-367, 2018 (DOI:https//doi.org/10.1016/j.ccell.2018.02.004)
DepositorNobuhiro Tanuma (Miyagi Cancer Center)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.

BRC mice in Publications

No Data